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Drye-Eye-University-Slide-V3

Dry Eye University

Dry eye disease is a multi-faceted eye condition that arises from various causes & may be treated with medicated drops, anti-inflammatory therapy, intense pulse light therapy, warm compresses, or Vectored Thermal Pulse therapy through LipiFlow. But, understanding which treatment provides effective results, how dry eye has been researched & redefined across the decades, and ultimately pinpointing the majority of dry eye cases will show that you’ve discovered a dry eye expert.

Evaporative dry eye is the most common form of dry eye disease, where advanced treatments provide long-lasting results that are noticed almost immediately. Not only can the right treatment restore the desired level of comfort to your eyes or even save time and money but, most importantly, ensure your eyesight remains healthy for years to come.

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DryEyeExperts-Slideshow

Evaporative Dry Eye is the #1 Cause for Dry Eye Disease

'Dry Eye' Is the Wrong Diagnosis for Millions.

The likely leading cause of "Dry Eye" is Meibomian Gland Dysfunction, and treating dry eye syndrome isn't so much guesswork as one might think. Unlike the standard use a warm compress & artificial tears, which are minimally effective, some treatments like LipiFlow are proving to treat Dry Eye disease successfully and accurately after countless studies & tests.


"Dry Eye" Is the Wrong Diagnosis for Millions.
Korb DR, Blackie CA.

Optom Vis Sci. 2015 Sep;92(9):e350-4. doi: 10.1097/OPX.0000000000000676.

PMID: 26204473

dry-eye-lipiflow-fb-cover

LipiFlow Technology

Although dry eye disease has been around for years, LipiFlow has changed the face of the disease from being challenging to mostly treatable. The vectored thermal pulsation from the LipiFlow treatment has shown to improve meibomian gland function and reduce dry eye symptoms quickly & efficiently.

Patients who receive a few LipiFlow treatments will notice significant changes in the comfort of their eyes as the treatment clears out the blocked meibomian glands. While severe cases of dry eyes may need some further diagnosis and/or medication, LipiFlow continues to produce long-lasting changes in patients with dry eye disease, unlike any other dry eye treatment.

How does LipiFlow compare to conventional compresses and hygiene therapy?

A single vectored thermal pulsation or LipiFlow treatment has shown to improve meibomian gland function and reduce dry eye symptoms, over 12 months when compared to a conventional, twice-daily, 3-month regimen of warm compress and eyelid hygiene therapy. Repeat LipiFlow treatments continued to prove greater improvements as well. Within 1 month, a LipiFlow Treatment was 50% more effective at targeting & diagnosing the dry eye symptoms with long-lasting results.

A new system, the LipiFlow, for the treatment of meibomian gland dysfunction.

A new system, the LipiFlow, for the treatment of meibomian gland dysfunction.

Lane SS, DuBiner HB, Epstein RJ, Ernest PH, Greiner JV, Hardten DR, Holland EJ, Lemp MA, McDonald JE 2nd, Silbert DI, Blackie CA, Stevens CA, Bedi R.

Cornea. 2012 Apr;31(4):396-404. doi: 10.1097/ICO.0b013e318239aaea.

PMID: 22222996

 

Case report: a successful LipiFlow treatment of a single case of meibomian gland dysfunction and dropout.

 

Case report: a successful LipiFlow treatment of a single case of meibomian gland dysfunction and dropout.

Korb DR, Blackie CA.

Eye Contact Lens. 2013 May;39(3):e1-3. doi: 10.1097/ICL.0b013e31824ccbda.

PMID: 22415153

 

Treatment for meibomian gland dysfunction and dry eye symptoms with a single-dose vectored thermal pulsation: a review.

Treatment for meibomian gland dysfunction and dry eye symptoms with a single-dose vectored thermal pulsation: a review.

Blackie CA, Carlson AN, Korb DR.

Curr Opin Ophthalmol. 2015 Jul;26(4):306-13. doi: 10.1097/ICU.0000000000000165. Review.

PMID: 26058030

 

A novel thermodynamic treatment for meibomian gland dysfunction.

A novel thermodynamic treatment for meibomian gland dysfunction.

Friedland BR, Fleming CP, Blackie CA, Korb DR.

Curr Eye Res. 2011 Feb;36(2):79-87. doi: 10.3109/02713683.2010.509529.

PMID: 21281063

 

Restoration of meibomian gland functionality with novel thermodynamic treatment device-a case report.

Restoration of meibomian gland functionality with novel thermodynamic treatment device-a case report.

Korb DR, Blackie CA.

Cornea. 2010 Aug;29(8):930-3. doi: 10.1097/ICO.0b013e3181ca36d6.

PMID: 20531168

 

thinking professional man slide

Warm Compresses - Treatment or Temporary Relief

Dry eyes have been commonly treated with the home remedy of a warm compress. The heat of the compress is supposed to help soften the secretions in the obstructed glands, and this would theoretically temporarily prevent further evaporation of the aqueous layer of the tear film. Or, in other words, help treat the evaporative dry eye.

However, this is based on the assumption that an obstructed gland can be treated with a certain low-level melting point, yet there are a couple of complications. Firstly, there is no specific temperature that would soften the obstructed glands as they vary in their melting points. Secondly, not every compress can reach the proper desired heat. Lastly, even if a compress could reach the desired heat, like the Bundle method, one must be careful when handling a warm compress when applying it to the eyes.

Although warm compresses might not directly treat evaporative dry eyes, using a warm compress is certainly better than nothing at all.

All Warm Compresses Are Not Equally Efficacious.

All Warm Compresses Are Not Equally Efficacious.

Murakami DK, Blackie CA, Korb DR.

Optom Vis Sci. 2015 Sep;92(9):e327-33. doi: 10.1097/OPX.0000000000000675.

PMID: 26164316

 

Warm compresses and the risks of elevated corneal temperature with massage.

Warm compresses and the risks of elevated corneal temperature with massage.

Blackie CA, McMonnies CW, Korb DR.

Cornea. 2013 Jul;32(7):e146-9. doi: 10.1097/ICO.0b013e318292a7b7.

PMID: 23665651

 

Warm compress induced visual degradation and Fischer-Schweitzer polygonal reflex.

Warm compress induced visual degradation and Fischer-Schweitzer polygonal reflex.

Solomon JD, Case CL, Greiner JV, Blackie CA, Herman JP, Korb DR.

Optom Vis Sci. 2007 Jul;84(7):580-7.

PMID: 17632305

Inner eyelid surface temperature as a function of warm compress methodology.

Inner eyelid surface temperature as a function of warm compress methodology.

Blackie CA, Solomon JD, Greiner JV, Holmes M, Korb DR.

Optom Vis Sci. 2008 Aug;85(8):675-83. doi: 10.1097/OPX.0b013e318181adef.

PMID: 18677234

Selected Research

Keratinized portions of the upper and lower lid margins don't make complete contact during deliberate blinking.

In Response to "Letter to Editor: Evidence Suggesting That the Keratinized Portions of the Upper and Lower Lid Margins Do Not Make Complete Contact During Deliberate Blinking".

Korb DR, Blackie CA.

Cornea. 2016 Mar;35(3):e6. doi: 10.1097/ICO.0000000000000720. No abstract available.

PMID: 26764886

Similar articles

Select item 26488155

In vivo detection of clinically non-apparent ocular surface inflammation in patients with meibomian gland dysfunction-associated refractory dry eye symptoms: a pilot study.

In a pilot study, high-magnification, laser-scanning in vivo confocal microscopy (IVCM) examined the palpebral conjunctivae and corneas of a few patients who suffer from a severe case of Dry Eye Disease and meibomian gland dysfunction (MGD). The study mentions that while treatments like LipiFlow, intraductal meibomian gland probing, and intense pulse light therapy improve symptoms, signs of active inflammation were still apparent. The study concludes that anti-inflammatory therapy may be a suitable option for the dry eye patients in the study. 

In vivo detection of clinically non-apparent ocular surface inflammation in patients with meibomian gland dysfunction-associated refractory dry eye symptoms: a pilot study.

Qazi Y, Kheirkhah A, Blackie C, Cruzat A, Trinidad M, Williams C, Korb DR, Hamrah P.

Eye (Lond). 2015 Aug;29(8):1099-110. doi: 10.1038/eye.2015.103.

PMID: 26088680 Free PMC Article

 

A Comparative Study Between an Oil-in-Water Emulsion and Nonlipid Eye Drops Used for Rewetting Contact Lenses.

A Comparative Study Between an Oil-in-Water Emulsion and Nonlipid Eye Drops Used for Rewetting Contact Lenses.

Guthrie SE, Jones L, Blackie CA, Korb DR.

Eye Contact Lens. 2015 Nov;41(6):373-7. doi: 10.1097/ICL.0000000000000138.

PMID: 26488155

 

Lid wiper epitheliopathy and dry eye symptoms.

Lid wiper epitheliopathy and dry eye symptoms.

Korb DR, Herman JP, Greiner JV, Scaffidi RC, Finnemore VM, Exford JM, Blackie CA, Douglass T.

Eye Contact Lens. 2005 Jan;31(1):2-8.

PMID: 15665665

Effect of using a combination of lid wipes, eye drops, and omega-3 supplements on meibomian gland functionality in patients with lipid deficient/evaporative dry eye.

Effect of using a combination of lid wipes, eye drops, and omega-3 supplements on meibomian gland functionality in patients with lipid deficient/evaporative dry eye.

Korb DR, Blackie CA, Finnemore VM, Douglass T.

Cornea. 2015 Apr;34(4):407-12. doi: 10.1097/ICO.0000000000000366.

PMID: 25651491

 

Psychometric properties and validation of the Standard Patient Evaluation of Eye Dryness questionnaire.

Psychometric properties and validation of the Standard Patient Evaluation of Eye Dryness questionnaire.

Ngo W, Situ P, Keir N, Korb D, Blackie C, Simpson T.

Cornea. 2013 Sep;32(9):1204-10. doi: 10.1097/ICO.0b013e318294b0c0.

PMID: 23846405

 

A novel lid seal evaluation: the Korb-Blackie light test.

A novel lid seal evaluation: the Korb-Blackie light test.

Blackie CA, Korb DR.

Eye Contact Lens. 2015 Mar;41(2):98-100. doi: 10.1097/ICL.0000000000000072.

PMID: 25503913

 

Debridement-scaling: a new procedure that increases Meibomian gland function and reduces dry eye symptoms.

Debridement-scaling: a new procedure that increases Meibomian gland function and reduces dry eye symptoms.

Korb DR, Blackie CA.

Cornea. 2013 Dec;32(12):1554-7. doi: 10.1097/ICO.0b013e3182a73843.

PMID: 24145633

 

Using goggles to increase periocular humidity and reduce dry eye symptoms.

Using goggles to increase periocular humidity and reduce dry eye symptoms.

Korb DR, Blackie CA.

Eye Contact Lens. 2013 Jul;39(4):273-6. doi: 10.1097/ICL.0b013e3182960ff9.

PMID: 23771008

 

The lid wiper contains goblet cells and goblet cell crypts for ocular surface lubrication during the blink.

The lid wiper contains goblet cells and goblet cell crypts for ocular surface lubrication during the blink.

Knop N, Korb DR, Blackie CA, Knop E.

Cornea. 2012 Jun;31(6):668-79. doi: 10.1097/ICO.0b013e31823f8d8c.

PMID: 22406942

 

Meibomian gland therapeutic expression: quantifying the applied pressure and the limitation of resulting pain.

Meibomian gland therapeutic expression: quantifying the applied pressure and the limitation of resulting pain.

Korb DR, Blackie CA.

Eye Contact Lens. 2011 Sep;37(5):298-301. doi: 10.1097/ICL.0b013e31821bc7c5.

PMID: 21617536

 

Nonobvious obstructive meibomian gland dysfunction.

Nonobvious obstructive meibomian gland dysfunction.

Blackie CA, Korb DR, Knop E, Bedi R, Knop N, Holland EJ.

Cornea. 2010 Dec;29(12):1333-45. doi: 10.1097/ICO.0b013e3181d4f366. Review.

PMID: 20847669

 

About vital staining of the eye and eyelids.

About vital staining of the eye and eyelids. I. The anatomy, physiology, and pathology of the eyelid margins and the lacrimal puncta by E. Marx. 1924.

Pult H, Korb DR, Blackie CA, Knop E, Marx E.

Optom Vis Sci. 2010 Oct;87(10):718-24. doi: 10.1097/OPX.0b013e3181f3217e.

PMID: 20729771

 

The lid margin is an underestimated structure for preservation of ocular surface health and development of dry eye disease.

The lid margin is an underestimated structure for preservation of ocular surface health and development of dry eye disease.

Knop E, Korb DR, Blackie CA, Knop N.

Dev Ophthalmol. 2010;45:108-22. doi: 10.1159/000315024. Review.

PMID: 20502031

Marx's line of the upper lid is visible in upgaze without lid eversion.

Marx's line of the upper lid is visible in upgaze without lid eversion.

Korb DR, Blackie CA.

Eye Contact Lens. 2010 May;36(3):149-51. doi: 10.1097/ICL.0b013e3181d9ee3c.

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Prevalence of lid wiper epitheliopathy in subjects with dry eye signs and symptoms.

Prevalence of lid wiper epitheliopathy in subjects with dry eye signs and symptoms.

Korb DR, Herman JP, Blackie CA, Scaffidi RC, Greiner JV, Exford JM, Finnemore VM.

Cornea. 2010 Apr;29(4):377-83. doi: 10.1097/ICO.0b013e3181ba0cb2.

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The diurnal secretory characteristics of individual meibomian glands.

The diurnal secretory characteristics of individual meibomian glands.

Blackie CA, Korb DR.

Cornea. 2010 Jan;29(1):34-8. doi: 10.1097/ICO.0b013e3181ac9fd0.

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The relationship between dry eye symptoms and lipid layer thickness.

The relationship between dry eye symptoms and lipid layer thickness.

Blackie CA, Solomon JD, Scaffidi RC, Greiner JV, Lemp MA, Korb DR.

Cornea. 2009 Aug;28(7):789-94. doi: 10.1097/ICO.0b013e318191b870.

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Recovery time of an optimally secreting meibomian gland.

Recovery time of an optimally secreting meibomian gland.

Blackie CA, Korb DR.

Cornea. 2009 Apr;28(3):293-7. doi: 10.1097/ICO.0b013e31818913b4.

PMID: 19387230

 

Meibomian gland diagnostic expressibility: correlation with dry eye symptoms and gland location.

Meibomian gland diagnostic expressibility: correlation with dry eye symptoms and gland location.

Korb DR, Blackie CA.

Cornea. 2008 Dec;27(10):1142-7. doi: 10.1097/ICO.0b013e3181814cff.

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A new model of central lid margin apposition and tear film mixing in spontaneous blinking.

A new model of central lid margin apposition and tear film mixing in spontaneous blinking.

Pult H, Korb DR, Murphy PJ, Riede-Pult BH, Blackie C.

Cont Lens Anterior Eye. 2015 Jun;38(3):173-80. doi: 10.1016/j.clae.2015.01.012.

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The role of heat in rubbing and massage-related corneal deformation.

The role of heat in rubbing and massage-related corneal deformation.

McMonnies CW, Korb DR, Blackie CA.

Cont Lens Anterior Eye. 2012 Aug;35(4):148-54. doi: 10.1016/j.clae.2012.01.001. Review.

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An evaluation of the efficacy of fluorescein, rose bengal, lissamine green, and a new dye mixture for ocular surface staining.

An evaluation of the efficacy of fluorescein, rose bengal, lissamine green, and a new dye mixture for ocular surface staining.

Korb DR, Herman JP, Finnemore VM, Exford JM, Blackie CA.

Eye Contact Lens. 2008 Jan;34(1):61-4. doi: 10.1097/ICL.0b013e31811ead93.

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Visually_Dry_Eye

Treatment of Dry Eyes

 

From Visually.